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Leptomeningeal disease (lmd), also known as leptomeningeal carcinomatosis, is a condition where cancer spreads to the brain, spinal fluid and leptomeninges, the thin layers of tissue around the … It occurs with cancers that are … Leptomeningeal metastasis—also called leptomeningeal carcinomatosis, leptomeningeal disease, or simply “lmd”—is the spread of cancer to a particular part of the brain called the leptomeninges. Leptomeningeal disease (lmd), or spread of cancer cells into the pia and arachnoid membranes encasing the brain and spinal cord, is associated with high symptom burden and poor survival at … It is also known as leptomeningeal carcinomatosis, leptomeningeal disease (lmd), leptomeningeal metastasis, meningeal metastasis and meningeal carcinomatosis. · diagnosing leptomeningeal disease can be challenging, not only because of the overlap of symptoms with those of brain metastases, but because of the testing process. · leptomeningeal disease (also known as lmd, leptomeningeal metastases, or lm) is cancer in your cerebrospinal fluid and in your leptomeninges, the membranes that surround your … · when cancer spreads to the cerebrospinal fluid surround the brain and spinal cord and/or the lining of the brain and spinal cord, it causes an aggressive disease called …