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Mutations in exon 7 and 9 of wt1 have been recurrently identified in … · map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) is a protein coding gene. The active enzyme is a homotetramer arranged … · the was gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in was patients. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal … · complete information for ass1 gene (protein coding), argininosuccinate synthase 1, including: Genecards - the human … Geneanalytics enables researchers to identify diseases related to their gene sets, and to discover disease mechanisms and specific disease markers. · the knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. Function, proteins, disorders, pathways, orthologs, and expression. · complete information for lpl gene (protein coding), lipoprotein lipase, including: Geneanalytics disease-related outputs … · this gene encodes pyruvate carboxylase, which requires biotin and atp to catalyse the carboxylation of pyruvate to oxaloacetate. Diseases associated with map4k4 include anus, imperforate and renal dysplasia. The genecards human gene database index: · this gene encodes a nuclear-localized e3 ubiquitin ligase. · wt1 is a tumor suppressor gene associated with the development of wilms tumor, from which it was named.