Function, proteins, disorders, pathways, orthologs, and expression. The genecards human gene database index: · map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) is a protein coding gene. Geneanalytics disease-related outputs rely on the information available in malacards, the most comprehensive human disease database. Genecards - the human gene compendium · the knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. · complete information for lpl gene (protein coding), lipoprotein lipase, including: Geneanalytics enables researchers to identify diseases related to their gene sets, and to discover disease mechanisms and specific disease markers. Mutations in exon 7 and 9 of wt1 have been recurrently identified in acute myeloid leukemia and associated with poorer prognosis and chemotherapy resistance. · wt1 is a tumor suppressor gene associated with the development of wilms tumor, from which it was named. · complete information for ass1 gene (protein coding), argininosuccinate synthase 1, including: The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. · this gene encodes a nuclear-localized e3 ubiquitin ligase. Diseases associated with map4k4 include anus, imperforate and renal dysplasia. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. · the was gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in was patients. · this gene encodes pyruvate carboxylase, which requires biotin and atp to catalyse the carboxylation of pyruvate to oxaloacetate.
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Function, proteins, disorders, pathways, orthologs, and expression. The genecards human gene database index: · map4k4 (mitogen-activated protein kinase kinase kinase kinase 4) is a protein...